Perfector Acting at the Cellular Level as an Antioxidant
The Nano Perfector signal resonates with the body’s own biological signals to restore cellular health, skin freshness and glow. The nano amperes’ microscopic size enters the skin triggering minimum resistance, empowering the signal with high definition clarity. The high definition nano signal infuses a steady flow of electrons through the treated area. The infused electrons act that an antioxidant at the cellular level. Antioxidants are necessary to counteract the oxidative damage accumulated throughout life that is believed to be a major contributing factor to aging and disease. Oxidation (loss of electrons) occurs in the cells’ mitochondria during the process of ATP formation (cell energy, also involved in DNA transformation). Free radicals are chemical species with an unpaired electron that attack the nearest stable molecules to "steal" their electrons. When the "attacked" molecule loses its electron, it becomes a free radical itself, beginning a chain reaction. Once the process is started, it can cascade, finally resulting in the disruption of a living cell. Nano amperes act as an antioxidant by infusing a steady stream of electrons through the cell with as little resistance as possible, donating electrons to the free radicals that were formed as a result of oxidation, during the ATP formation. This process of nano amperes donating electrons to the free radicals ends the electron "stealing" chain reaction caused by free radicals. Nano amperes act as scavengers helping to prevent cell and tissue damage that may ultimately lead to cellular damage and disease. The nano amperes’ antioxidant action allows for ATP formation minus the build up of free radicals that can ultimately destroy the cells. ATP is the chemical energy that the cell needs to fulfill its normal biological functions. Functions that lead to the production of collagen, elastin and other elements necessary for lifting, firming, and youthful freshness of skin after a Perfector treatment.
Transformation through Nanotechnology
One may also envision the repair of damaged cells as an electromagnetic rearrangement of cellular elements that transform aged skin by restoring the appearance of youth. Nanotechnology has shown us that atoms arranged in one way make coal; rearranged in a different way they make diamonds. Rearranging the atoms in dirt, water and air allows us to make fresh strawberries. Similarly, aged skin reflects one arrangement of cellular elements; rearranging these elements leads to a transformation – what was aged before becomes luminous, lifted and youthful.
Perfector’s High Definition Signal
The Perfector signals were formulated on the basis of research examining cellular relationships and the broad issues of biological communications. Researchers have earned the Nobel Prize for their contribution in identifying aspects of the web-like structure of cellular signals. The translation of this intricate biological language has proven to identify hidden solutions for various physiological events, including aging. Perfector is the only computerized device that utilizes complex waveforms and adjustable voltage to deliver a high definition signal designed to achieve resonance with cellular biological processes. Perfector uses specifications shown by international research to act as an antioxidant as well as increase:
- collagen
- elastin
- cellular proliferation
- ATP
- epidermis thickening
- scar healing
The Perfector signals are based on research that examines cellular relationships and the broad issues of biological communication. Researchers have earned the Nobel Prize for their contribution in identifying aspects of the web-like structure of cellular signals. The translation of this intricate biological language has proven to identify hidden solutions for various physiological events, including aging.
Perfector technology incorporates the latest scientific advances:
- Specifications associated with collagen increase and natural tissue expansion (Santos et al, 2005).
- Proprietary waveforms consistent with Neher's findings of cellular biological responses (Edwin Neher, Nobel Prize, 1991), enhanced collagen, and elastin production (Chi, 2003).
- Proprietary waveforms for electromagnetic detoxification (London University).
- Specifications that increase cellular energy (Cheng, 1982) as well as cellular communication (Martin Rodbell, Nobel Prize 1994 ).
- Voltage automatically adjusts to skin resistance.
Perfector rejuvenation is dramatic in one treatment but a series of treatments is recommended for long lasting results.
Increased collagen and elastin production as well as the production of Adenosine Trisphosphate (ATP) have been documented by research. ATP plays an important role in cellular energy transport, transformations, and enzyme regulation as the protein kinase. Go to www.nobelprize.org for more information about the role that proteins play in biological functioning.
RESEARCH QUOTES:
"The treatment group showed: a homogeneous epithelial regeneration more compact and eosinophitic collagen more evident healing scar epidermis thickening. The amount of fibroblasts (cells that produce collagen and elastin) was greater than the one in the untreated group."
--Santos VNS et al, 2004
"Channels in biological membranes open and close stochastically in an all-or-none manner. The fact that similar records could be obtained both in our Gottingen laboratory and in the laboratory of Charles F. Stevens at Yale gave us confidence that they were not the result of some local demon, but rather signals of biological significance."
--Edwin Neher, 1991 Nobel Prize in Medicine and Physiology.
Quantifiable results over the course of 20 days:
10% increase in the production of natural collagen
48% increase in natural elastin production
38% increase in blood circulation
--Chi, 2003 Washington University
In 1982, Ngok Cheng studied changes in the cells using electron microscopy following the application of a wide range of currents. This technique enabled him to observe the changes in the cellular mechanics. His results indicated that current between 50 and 500 micro-amperes causes an increase in mitochondria and an increase of ATP levels by 300 to 500 percent. Cheng also noted that at this level, there was an increase in protein synthesis and gluco-neogenesis.
--N. Cheng, 1982
"Of particular interest is the fact that all three types of multimeric proteins are subject to regulation by either GTP (G-proteins and tubulin) or ATP (actin). Based on evidence accumulated over the past decade, cytoskeletal proteins are connected in some manner to a variety of signaling systems that adhere to the cytoskeletal matrix. These components form web-like structures that possibly interact in a flickering manner in response to activation of membrane receptors, including those that are growth promoting."
--Martin Rodbell, Nobel 1994 Nobel Prize in Medicine and Physiology
Some of the international research studies related to nano amperes or micro amperes that have shown us impressive results are noted below: For more info on relevant studies please go to the Perfector References section.
1. Xanya Sofra-Weiss, Ph.D. combines data from the listed references, enriching our understanding of micro electricity in order to form hypotheses for future research. Although micro electrical procedures have yet to be recognized as mainstream medical treatments, recent studies based on electronic advances reliably replicate results pointing towards the cability of micro electricity to resonate the wisdom of our inherent capacity for self regeneration and healing.
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2. Bok Y. Lee, MD, FACS, Alfred J. Koonin, M.B., Ch, B., Ph.D., FRCS, Keith Wendell, Ph.D., John Hillard, RN (2005) used nano amperes and ultra low frequencies to treat 25 chronic skin ucers in patients in a hospital setting. 92 % of the lesions were stages III or IV. The age of the lesions varied from 6 to 60 months with an average of 18.5 months. 100% of the lesions healed in an average of 48 hours of treatment, i.e. an average of 16 days. Average time of healing was 48 hours of treatment over 16 days. Surgical debridement was unnecessary as the necrotic tissue appeared to disappear spontaneously. The ages of the patients ranged between 20 and 85 years of age. The patients were divided into three age groups, viz., 20 to 50, 50 to 70 and greater than 70 years of age. The rate of healing was measured in cm2/day. The length of time of treatment was also compared to the duration of the lesion. Many studies have shown that the rate of wound healing of an individual is directly proportional to their age. From this study it can be seen that treating chronic skin ulcers with the ultra-low current device eliminates the age factor by equalizing the healing rate at all ages. The only limiting factor in healing time with this method seems to be the duration of the lesion. This study therefore suggests that treatment with the ultra-low current device eliminates the restrictions that aging brings to the healing process. None of the healed lesions has shown any sign of recurrence to date after a period ranging from six to eighteen months.
PDF Article
3. Yi-lo Lin, DVM, MSc; Hugo Moolenaar, PhD; P. René van Weeren, DVM, PhD; Chris H. A. van de Lest, PhD (2005) report that application of microcurrent of moderate intensity increased cell proliferation and DNA content, with greater increases with multiple versus single application. Application of micro-current of moderate intensity once or twice increased protein content.
PDF Article
4. Vilma Natividade Silva Santos, Lydia Masako Ferreira, Edith Kawano Horibe4, Ivone da Silva Duarte (2004) report that in the histological evaluation of the group treatment with ultra low frequencies a homogeneous epithelial regeneration, more evident healing scar, and epidermis thickening were seen. The amount of fibroblasts was greater than the control (untreated) group besides presenting more compact and eosinophitic collagen.
PDF Article
5. Chi Y Emil (two research studies 1999 and 2003): "The fact that this technology works in harmony with the body is evident. Examination of skin tissue treated with micro-current showed a 45% increase in the number of elastin fibres in the dermis, and the length of the fibres on average doubled. The collagen thickness in connective tissue increased 10%, and the number of blood vessels increased by 35%. The application of micro-current to skin and tissue produced a firmer and tighter feeling on the skin surface… …the redness, irritation and inflammation of surgically traumatized tissue could be decreased significantly when treated with micro-current. Related to this, the build up of hardened collagen that makes up scar tissue was noted to be three to five times less in tissue treated without micro-current. "
6. 29th Seminar of the Austrian Society for Surgical Research. J. Müller, B. Kapeller, U. M. Losert, K. Macfelda Berlin Heart AG, Berlin, Deutschland; Core Unit for Biomedical Research, Medical University Vienna, Vienna, Austria. "As known from dermatology and orthopaedics, electrical micro-current application can modulate the collagen composition (collagen I and III) of the extracellular matrix."
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7. Mel C Siff PhD (2000) Evidence implies that (MICS – Micro-current stimulation) elicits biochemical changes associated with enhanced adaptation, growth and repair. Since MICS appears to operate more on the basis of resonant attunement of the stimulus to cellular and subcellular processes, the specific therapeutic effects are determined by how efficiently the stimulation parameters match the electrical characteristic of the different cells, in particular, their impedance at different frequencies.
PDF Article
8. Cheng N, Van Hoff H, Bockx E. (1982) who studied the effect of electric currents on ATP generation protein synthesis, and membrane transport, proved that a low amperage current stimulates the physiologic activity of damaged cells.
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relevant articles
1991 Neher Nobel Lecture
Micro-current Electrical Therapy Heals a Recalcitrant Wound in a Horse
Predicting Neuron Spikes
PERFECTOR CLINICAL AND EXPERIMENTAL RESEARCH:
2006: |
Clinical Research: Effects of Perfector nano amperes on skin and facial muscles of human subjects. Data collected from 48 human subjects reporting visible differences after application of nano amperes. |
2006: |
Experimental Research: Comparison of Perfector micro amperes with nano amperes in reducing wrinkles and lifting sagging muscles of 10 human subjects. |
2006 Experimental Study Abstract:
Perfector programs with micro amperes were compared with Perfector programs with nano amperes by Xanya Sofra-Weiss, Ph.D, Director of Research for Arasys Perfector. This 2006 double bind study used a within subjects design. Ten subjects received five 30-minute Perfector treatments with two nano ampere programs (muscle lifting and wrinkle reduction) on one side of their faces and five treatments 30-minute Perfector treatments with two micro ampere programs (muscle lifting and wrinkle reduction) on the other side of their faces. Treatments were offered every four days for a total of 20 days. Two nano ampere and two micro ampere programs were randomly assigned on the first four Perfector buttons. Neither the technician nor the subjects were aware as to which button was a nano ampere program and which was micro ampere. The side of the face was also randomized so that five of the subjects received nano ampere on the right side of their faces and five of the subjects received the nano ampere on the left side of their faces. Similarly, five of the subjects received the control micro ampere on the left side of their faces and five of them received the control micro ampere on the right side of their faces.
Measure: Face lift and wrinkle removal evaluated by two independent judges immediately after the fifth treatment and six weeks later. Neither judge was aware of which system was used on which side of the face. Judgement was based on before and after digital pictures taken from the same angle and by looking live at subjects before and after results. Digital pictures included full face, left / right eye and mouth close ups.
Results: The mean percentage taken from the two independent judges was used for statistical analysis comparing micro amperes with nano amperes. The Chi Square Test revealed significantly better results with the two nano programs. (Immediately after the five treatments: face lift p<0.001; wrinkle reduction p<0.001. Six weeks after treatment completion: face lift p< 0.001; wrinkle reduction p< 0.001)
2005: |
Experimental Research: Effects of square and rectangular waveforms on skin and facial muscles of human subjects. Research has not been released to avoid disclosure of pertinent proprietary information. |
2004: |
Clinical Research: Effects of Perfector specific waveforms and frequencies combination on pigmentation and melasma of human subjects. |
2004: |
Experimental Research: Comparison of the Perfector with a different micro-current system revealed that Perfector was more efficient in reducing wrinkles and lifting sagging muscles of human subjects. |
2004: |
Experimental Research: Replication of an earlier study in 2004. Comparison of the Perfector with a different micro-current system revealed that Perfector was more efficient in reducing wrinkles and lifting sagging muscles of human subjects. |
2004 Experimental Studies Abstract:
Two double bind studies compared the Perfector to two other micro-current systems that were available in the USA market. Both 2004 studies used a within subjects design. Both studies (first study n= 6 subjects / second study n=16 subjects) compared Perfector with a different micro-current machine. Subjects in both studies received ten 45 minutes Perfector treatments on one side of the face and ten 45 minutes treatments with a different micro-current machine on the other side of their face. Treatments were offered every 4 days for a total of 40 days. The side of the face was also randomized so that half of the subjects received the Perfector on the right side of their faces and half of the subjects received the Perfector on the left side of their faces. Similarly, half of the subjects received the control micro-current machine on the left side of their faces and half of them received the control micro-current machine on the right side of their faces. Statistical results revealed significantly better results with the Perfector. (Immediately after the 10 treatments: face lift p<0.01; wrinkle reduction p<0.01. Three weeks after: face lift p< 0.001; wrinkle removal p< 0.001).
Conclusion: (1) Perfector is more efficient in lifting sagging muscles and reducing wrinkles than the control micro-current machine; (2 Perfector results last longer than those of other micro-current machines.
2003: |
Clinical research: Comparing the effectiveness of different waveforms and frequencies in reducing wrinkles and lifting sagging muscles. Specification that enhance detoxification and absorption of cosmetic products have also been clinically tested. Special attention was given to waveforms that appeared to enhance skin glow, tissue thickness and freshness. Research has not been released to avoid disclosure of pertinent proprietary information. |
2003: |
Clinical study: Clinical evidence that Perfector helps sun damage, rosacea and acne has been documented by two different clinical studies (Khasak. MD; Alona Yantunen , NY 2003; Vadim Cherny , Alona Yantunen, NJ 2003) |
2002: |
Experimental Research: Experimental study comparing the effects of specific micro-current frequencies on rosacea with three patient samples: Experimental group – Micro-current only; control group – Micro-current and meds; control group – meds only. |
ARASYS PERFECTOR EMPIRICAL ELECTRONIC RESEARCH:
2000 - 2007: |
Ks Electronics, UK, have been working on the Perfector waveforms and the hardware necessary for the Perfector upgrades. They are presently working in designing a new motherboard and developing new waveforms for the Pico Perfector. |
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